Studies show how fruit, veges reduce cancer

Dec 9th, 2007 | By Michael Fraser | Category: In the News, Latest News

JUST three servings a month of raw broccoli or cabbage can reduce the risk of bladder cancer by as much as 40 per cent, researchers report.Other studies show that dark-colored berries can reduce the risk of cancer too - adding more evidence to a growing body of research that shows fruits and vegetables, especially richly coloured varieties, can reduce the risk of cancer.
Researchers at the Roswell Park Cancer Institute in Buffalo, New York, surveyed 275 people who had bladder cancer and 825 people without cancer. They asked especially about cruciferous vegetables such as broccoli and cabbage.

These foods are rich in compounds called isothiocyanates, which are known to lower cancer risk.
The effects were most striking in non-smokers, the researchers told a meeting this week of the American Association of Cancer Research in Philadelphia.
Compared to smokers who ate fewer than three servings of raw cruciferous vegetables, non-smokers who ate at least three servings a month were almost 73 per cent less likely to be in the bladder cancer group, they found.
Among both smokers and non-smokers, those who ate this minimal amount of raw veggies had a 40 per cent lower risk. But the team did not find the same effect for cooked vegetables.
“Cooking can reduce 60 to 90 per cent of ITCs, (isothiocyanates),” Dr Li Tang, who led the study, said.
A second team of researchers from Roswell Park tested broccoli sprouts in rats.
They used rats engineered to develop bladder cancer and fed some of them a freeze-dried extract of broccoli sprouts. The more they ate, the less likely they were to develop bladder cancer, said Dr Yuesheng Zhang, who led the research.
They found the compounds were processed and excreted within 12 hours of feeding. That suggests the idea that compounds are protecting the bladder from the inside, Dr Zhang said.
“The bladder is like a storage bag, and cancers in the bladder occur almost entirely along the inner surface, the epithelium, that faces the urine, presumably because this tissue is assaulted all the time by noxious materials in the urine,” Dr Zhang said.
In a third study, a team at The Ohio State University fed black raspberries to patients with Barrett’s esophagus, a condition that can lead to esophageal cancer.
Black raspberries, sometimes called blackberries or blackcaps, are also rich in cancer-fighting compounds.
Ohio State’s Laura Kresty and colleagues fed 32 grams of freeze-dried black raspberries to women with Barrett’s esophagus and 45 grams to men every day for six months.
They measured urine levels of levels of two compounds - 8-isoprostane and GSTpi - that indicate whether cancer-causing processes are going on in the body.
Kresty said 58 per cent of patients had marked declines of 8-isoprostane levels, suggesting less damage, and 37 per cent had higher levels of GSTpi, which can help interfere with cancer causing damage and which is usually low in patients with Barrett’s.

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